Theoretical model

An X-linked meiotic drive allele has strong, recessive fitness costs in female Drosophila pseudoobscura

We measured the effects of a natural gene drive, _Sex Ratio_ (_SR_), on fitness in _Drosophila pseudoobscura_. We find that _SD_ is very costly, especially when homozygous, and that it also has transgenerational effects on offspring fitness and sex ratio. Using a model, we show that these effects may explain the frequency and clinal patterns of _SR_ in nature.

Fitness consequences of the selfish supergene Segregation Distorter

We measured the effects of a natural gene drive, _Segregation Distorter_ (_SD_), on fitness in _Drosophila melanogaster_. We find that _SD_ is very costly, especially when homozygous, and that it also has transgenerational effects on offspring fitness and sex ratio. Using a model, we show that these effects may explain the puzzling rarity of _SD_ in nature.

Evolutionary simulations of Z-linked suppression gene drives

This paper presents eco-evo simulations investigating the feasibility of a newly-proposed type of gene drive, the _W_-shredder. _W_-shredders might someday be used to control populations of pests and pathogens that have _ZW_ sex determination, such as Lepidopteran pests, parasitic trematodes, and cane toads.

Evolution of female choice under intralocus sexual conflict and genotype-by-environment interactions

We use theoretical models to examine the evolution of female choice when there is both intralocus sexual conflict and local adaptation. We show that IASC can weaken female preferences for high-condition males -- or even cause a preference for males in low condition -- depending on the relative benefits of producing well-adapted sons versus daughters. We discuss the relevance of our results to conservation genetics and empirical evolutionary biology.

Bet hedging via multiple mating: a meta-analysis

Polyandry has been hypothesized to allow females to “bet hedge” against mating only with unsuitable mates, reducing variance in offspring fitness between members of a polyandrous lineage relative to a single‐mating one. Theoretically, this reduction …

Coevolutionary dynamics of polyandry and sex-linked meiotic drive

Segregation distorters located on sex chromosomes are predicted to sweep to fixation and cause extinction via a shortage of one sex, but in nature they are often found at low, stable frequencies. One potential resolution to this longstanding puzzle …

Conditional helping and evolutionary transitions to eusociality and cooperative breeding

The nonreproductive helpers of many arthropod, bird and mammal species are a perennial puzzle for evolutionary biologists. Theory and evidence suggests that helping is favored by high relatedness between social partners and by certain ecological …

The evolution of genomic imprinting: Costs, benefits and long-term consequences

Genomic imprinting refers to a pattern of gene expression in which a specific parent's allele is either under-expressed or completely silenced. Imprinting is an evolutionary conundrum because it appears to incur the costs of diploidy (e.g. presenting …

Caste load and the evolution of reproductive skew

Reproductive skew theory seeks to explain how reproduction is divided among group members in animal societies. Existing theory is framed almost entirely in terms of selection, though nonadaptive processes must also play some role in the evolution of …

Crozier’s paradox revisited: maintenance of genetic recognition systems by disassortative mating

Organisms are predicted to behave more favourably towards relatives, and kin-biased cooperation has been found in all domains of life from bacteria to vertebrates. Cooperation based on genetic recognition cues is paradoxical because it …