Mitochondrial DNA

Mother’s curse and indirect genetic effects: do males matter to mitochondrial genome evolution?

We argue that the effects of mitochondrial DNA on a male phenotype can respond to selection, provided that males interact with their female 'mitochondrial relatives', and that the male phenotype affects female fitness. We present experimental evidence that female fitness depends on the mitochondrial DNA carried by interacting males, and discuss the implications for 'mother's curse'.