Mitochondrial DNA

Sibling rivalry versus mother's curse: can kin competition facilitate a response to selection on male mitochondria?

We find evidence that the mitochondrial DNA carried by _Drosophila_ larvae affects the fitness of other cohabiting larvae -- a mitochondrial 'indirect genetic effect'. This result implies that the effects of mitochondrial DNA on the phenotype of males (specifically, male larvae) may have evolutionary consequences, in contrast to the received wisdom that mtDNA inside males is 'invisible to selection' due to maternal inheritance of mtDNA.

Mother’s curse and indirect genetic effects: do males matter to mitochondrial genome evolution?

We argue that the effects of mitochondrial DNA on a male phenotype can respond to selection, provided that males interact with their female 'mitochondrial relatives', and that the male phenotype affects female fitness. We present experimental evidence that female fitness depends on the mitochondrial DNA carried by interacting males, and discuss the implications for 'mother's curse'.